Breaking News: Model Release for SECRET Competition
Model Release: to access go to link
Statistical Emulation for Computational Reverse Engineering and Translation
Welcome to the SECRET international competition in cardiac modelling
This competition aims to assess computational tools for accurate, robust and computationally efficient inference of unknown parameters in complex cardiovascular biophysical models from physiological data. We would expect most of the submitted techniques to be based on surrogate modelling and emulation. We will provide two state-of-the-art computational fluid dynamics (CFD) models of the pulmonary and systemic circulation, respectively. These models will serve as benchmark examples to assess your methods for fast model parameter inference and uncertainty quantification (UQ). To evaluate the performance of your method, we will provide synthetic data simulated from the aforementioned CFD models with pre-set parameter values, subject to additive observational noise. The true parameter values will be revealed after all participants have submitted their answers.
You will be invited to submit (i) estimates of the biophysical parameters, (ii) the corresponding “best” data prediction and (iii) a measure of estimation uncertainty (standard deviation). The assessment of your method will be based on accuracy and UQ in parameter and function space.
The competition consists of two stages.
Stage one: you will be given the opportunity to familiarise yourselves with the model and construct a statistical emulator for the quantity of interest well in advance of the data being released.
Stage two: after the data have been released, you will be given a limited time interval (one week) to conduct the parameter estimation and UQ analysis and submit your predictions. This limitation is with clinical translation in mind, to mimic clinical practice and decision support.
The participants with the best three entries for each model will be invited to disseminate their work in a one-day conference hosted at the University of Glasgow. The best three entries for each model will also receive a certificate and a financial award, details of which will be announced later. The final goal of the competition is a research publication in a high-impact journal with all six selected submissions, which will provide a platform to disseminate the statistical methods and results obtained. The independent assessment of your method by the competition organisers based on an objective gold standard will be an opportunity for you to promote your work and increase its visibility.
Please refer to the timeline below for all important dates.
16th January – Competition announcement call out
20th March – Release of the models and the challenge description
1st September – Release of the data
8th September – Deadline for participants to submit their predictions
18th September – Organisers make the correct answers available and release the best three entries for each model
23rd October – Conference day
23rd October onwards – Work towards a joint publication
We will reimburse international travel costs for the winners (separately for both models) and will provide further travel support, though capped at UK national travel cost levels, for the 2nd and 3rd places (again separately for both models). We will also provide accommodation for the participants with the best six entries (places 1-3, for both models).
IMPORTANT: Could all interested participants record their interest via the Eventbrite link on the right
This competition is organised as part of the SofTMech Statistical Emulation and Translation Hub: https://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/T017899/1.
- Event Organiser: Mihaela Paun from the University of Glasgow
- Co-organisers: Dirk Husmeier, University of Glasgow, Mitchel Coleback, University of California,Mette Olufsen and Alyssa LaPole, North Carolina State University
What happened at the CardiARC Zone
Tue, 23 Aug 2022 12:59:00 BST
As part of the ARCADIA festival SofTMech presented the CardiARC Zone on the 17th September 12.00 - 15.00 in the new Advanced Research Centre at the University of Glasgow.(ARC). We ran some fun competitions to test knowledge of the heart. Our Virtual Reality (VR) tours of the heart in the ARC's VR suite proved very popular and we we were sold out; full report....
SofTMech Team Awarded BHF Project Grant on Tetralogy of fallot
Wed, 15 Jun 2022 09:46:00 BST
A team of researchers from the SofTMech Centre has been awarded a three-year British Heart Foundation project grant on “A modelling study of right ventricular function in repaired tetralogy of fallot for predicting outcome and impact of pulmonary valve replacement” read more ......
Cardiac Imaging in SARS Coronavirus disease-19 (CISCO-19) published in Nature
Mon, 23 May 2022 13:37:00 BST
Cardiac Imaging in SARS Coronavirus disease-19 (CISCO-19) published in Nature. The project was awarded £47,940 in the Chief Scientist Office Rapid Research in Covid-19 (RARC-19) funding call to lead a project to investigate Cardiac Imaging in SARS Coronavirus disease-19 (CISCO-19) read more .........
What happened at the PhD Poster Competition on the 31st May
The event was an in-person Poster competition open to PhD students from SofTMech and CMALS. 28 people registered for the event; 17 presented posters.
After two years of the pandemic this event gave a valuable opportunity to at last ask questions in person, for discussion and perhaps just as importantly to meet some colleagues for the first time. Students participated in the event from the University of Glasgow Schools of Mathematics and Statistics, Biomedical Engineering, Ultrasonic Engineering and Computational Mechanics. Students came from the University of Strathclyde departments of Mathematics & Statistics and Biomedical Engineering.
Prior to the event the students arrived early to set up their posters. The event was opened by Dr Sean McGinty, Director of CMALS. A series of 1 min flash presentations, where each student had to give an overview of their poster by displaying a maximum of 2 PowerPoint slides, set the scene for the poster viewing. One of the students even gave directions to where his poster was; it worked as he finished 2nd !
The posters were judged by a combination of a panel of members of staff and also by the students themselves, who were each allowed one vote for their favourite poster. The standard of posters was high across the board. Certificates and vouchers were awarded to the best three posters.
1st Prize: Tahani Al Sariri
Hyperthermic temperature and interval induced by magnetic nanoparticles transport in vascularised tumours
2nd Prize: Yuzhang Ge
Gaussian Process for Predicting Left Ventricular Displacements in Diastole
3rd Prize: Alistair McQueen
Computational modelling reveals an intricate interplay between drug release rate and dose on restenosis
Thanks go to the panel of academics for judging the posters, the library for turning around the printing of the posters, catering for the excellent scones, and all the attendees.
We hope the experience of this event will help all the students as they progress in their careers.
Calendar of Events
- Next Research Meeting (Hybrid) Wednesday 14th December 311B
Research Associated appointed
Mon, 01 Aug 2022 15:53:00 BST
Update: We have recruited the Research Associate details to follow soon. The project is funded by the British Heart Foundation (mathematical modelling right ventricular function in repaired Tetralogy of Fallot for predicting outcome and impact of pulmonary valve replacement) working with Hao Gao, Mark Danton, Colin Berry, Xiaoyu Luo, Nick Hill, and Dirk Husmeier.
INTERNATIONAL WORKSHOP: A SYMPOSIUM ON CONTINUUM QUESTIONS: 12th and 13th May 2022
The Schools of Mathematics & Statistics at the University of Glasgow is organizing the
International Workshop: "A symposium on Continuum Questions"
The workshop is aimed at providing a two-day symposium where the state of the art and future perspectives concerning continuum mechanics and its applications will be discussed.
See link on right for full details and how to register
Attending an academic conference and networking
Attending an academic conference and networking: 24.03.22
Our first informal training event discussed academic conferences, covering:
- what actually happens at an academic conference?
- what can I hope to get out it?
- how do I network effectively?
The event also included a practical exercise on preparing an elevator pitch for networking with senior academics.
A recording of the event can be accessed from the link on the right hand side of the screen.
5th Soft Tissue Workshop 1-3rd June 2021
Tue, 04 May 2021 21:01:00 BST
The 5th St. Andrews Soft Tissue workshop took place on Tues. 1st June to Thurs. 3rd June. It was supported by ICMs. There were 100 registered delegates. The three day workshop programme covered the themes of Cardiac Modelling, Multiscale Modelling, Respiration and Circulation, Cancer and Mechanobiology. There were 6 plenary talks,28 talks & a poster session in sococo, preceded by one-minute presentations by the poster delegates. Recordings of all 6 plenary talks can be viewed via link.
SofTMech Training Day 28.01.22
Mon, 31 Jan 2022 12:21:00 GMT
On Friday Jan 28th 2022 The SofTMech Training committee hosted a (virtual) half day training workshop on the theory and practice of the Finite Element Method. To view further details including how to access the recorded talks click here .....
CMALS "Show & Tell " Event:Wed. 28th April
Wed, 10 Mar 2021 15:40:00 GMT
CMALS (The Centre for Mathematics Applied to the Life Sciences is a joint UoG-Strathclyde Centre) held a virtual ‘Show & Tell’ event on Wednesday 28th April. Members of staff from both Unis. gave 5 minute talk (3 slides) There were also talks from Non-mathematicians from across the universities and beyond (e.g. clinicians and industrialists). ..
On-line St. Andrews SofTMech Tissue Modelling Workshop: 1st - 3rd June 2021
Tue, 28 May 2019 13:11:00 BST
The final Day of the 2019 Soft Tissue Modelling Workshop was held on Friday 7th June; the SofTMech Workshop committee would like to thank all the delegates for coming to take part in the workshop. An A-Z of the workshop can be viewed via the link to the right. Due to COVID-19 the 5th St. Andrews workshop will be held on-line from the 1st to 3rd June 2021 watch this space for further details read more .....
TRAINING DAY JANUARY 8th 2021
Mon, 23 Nov 2020 10:54:00 GMT
On Friday 8th January 2021 an on-line training day organised by Professor Dirk Husmeier and Dr Peter Stewart was held. 51 people registered, a mixture of CIs, RAs and PhD students from the University of Glasgow, University of Plymouth, Terumo Aortic, POLIMI, MIT, EPFL and North Carolina State University. There were sessions on Mathematical Modelling Principals, Dark data, Parameter estimation and uncertainty quantification see more .............
Impact of COVID-19
Fri, 20 Mar 2020 12:07:00 GMT
Because of the rapidly changing COVID-19 virus pandemic, we have decided to postpone all in person events planned for the next few months. The Fifth Soft Tissue workshop due to have been held in St Andrews in June of this year will be postponed until the summer of 2021. We will continue our internal Wednesday Research Meetings on-line. SofTMech wishes everyone to remain safe in these challenging times and our thoughts are with POLIMI and MIT and all our collaborators in other countries.
SofTMech Patient Participation Day 20th May 2019, Golden Jubilee Conference Hotel - Innovation center
Mon, 20 May 2019 13:04:00 BST
SofTMech held a Patient Participation Day at the Golden Jubilee Conference Hotel Innovation Centre on Monday 20th May 2019. A big thank you to all the patients that attended. A slide show of the event and the presentations can be viewed via link to the right read more ....
SIG Event on Fluid Mechanics of the Eye: Tuesday 26th to Wed 27th March 2019
Thu, 31 Jan 2019 12:09:00 GMT
This event will bring together a group of modellers to work on problems related to the fluid mechanics of the eye. It follows as part of a series of meetings funded by the UK Fluids Network (past meetings at Imperial, Oxford, Manchester) Please click to read more.
SOFT TISSUE MODELLING WORKSHOP, GLASGOW, JUNE 5-7 2019
Mon, 04 Jun 2018 13:05:00 BST
The 4th workshop took place from Wednesday 5th to Friday the 7th June. The workshop focused on the most recent advances in the field of soft tissue mechanics, with a clear vision of the landscape of multiscale soft tissue modelling and both fundamental and translational research. Due to COVID-19 the 5th workshop will be postponed for 1 year and be held in June 2021 read more........
SofTMech Industry Dialogue
Thu, 10 May 2018 14:28:00 BST
SofTMech held an Industry Diaolgue on the 24th November, 2017. The aim of the event was to create a dialogue through which attendees can identify ways in which their organisations can gain economic value/competitive advantage through application of the centre’s research to their business challenges.
Cside 2018: Competitive statistical inference for differential equations 26th Nov 2018, University of Glasgow Mathematics and Statistics Building, Room 311B
Mon, 03 Sep 2018 13:15:00 BST
Differential equations are a powerful way of providing an observed system a mathematical description. However, the act of inferring the parameters that govern the equations from noisy data, especially in a timely fashion, is challenging. The main objective of Cside is to assess in a competitive setting what inference methods in this area are currently the state of the art read more..........
Visit by Professor Rajagopal
Thu, 01 Nov 2018 13:12:00 GMT
Professor Rajagopal will visit from the 2nd to the 6th November. During the visit, Prof. Rajagopal will give an applied maths seminar to the whole School and SofTMech. He will SofTMech have individual meetings with various SofTMech members. The discussion will be focused on the reconstruction of new constitutive laws. He will also talk to various other members of SofTMech interested in constitutive modelling, and aortic dissection read more ......
Five EPSRC Maths-Healthcare Centres Meeting, University of Glasgow, 19th-21st Sept. 2018
Fri, 22 Jun 2018 10:22:00 BST
The FIVE EPSRC Maths-Healthcare Centres (Cambridge, Exeter, Glasgow, Imperial and Liverpool) gathered together on the 19th to the 21st September at the University of Glasgow to exchange success stories and share experiences, and more importantly to consider future funding read more...
FIRST Joint SofTMech Liverpool LCMH Meeting
Thu, 10 May 2018 14:43:00 BST
On the 4th April, 2018 the first of two meetings was held between SofTMech and Liverpool CMH in Glasgow. The second joint meeting will be held in Liverpool on Thursday 30th August; see adjacent tile. For more on the first meeting.......
Charles Taylor from HeartFlow Visit Wed. 7th November
Thu, 01 Nov 2018 12:06:00 GMT
Dr Charles Taylor will make a short visit on Wed. 7th Nov., starting with a short tour of the Maths and Statistics department at 11.30am, followed by lunch in the Western Infirmary lecture Theatre (WILT) foyer, his seminar talk at 1pm in the WILT is entitled “Noninvasive assessment of the functional significance of coronary heart disease using CT and computational fluid dynamics” read more .........
Fellowships for SofTMech staff and students
Fri, 27 Aug 2021 12:26:00 BST
SofTMech staff and students have been awarded Fellowships; Dr Cicely Macnamara has been appointed to a three-year Rankin-Sneddon Fellowship in the School of Mathematics and Statistics at the University of Glasgow, from September 2021. SofTMech students Debao Guan and Jay Mackenzie have been awarded one-year Post-PhD Research Assistantships in Mathematics and Statistics at Glasgow read more........